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Ribozyme and the mechanisms that underlie RNA catalysis

Timothy J. Wilson,Yijin Liu,David M. J. Lilley

Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 2,   Pages 178-185 doi: 10.1007/s11705-016-1558-2

Abstract: Mechanistically most fall into one of two classes, using either metal ions or general acid-base catalysis

Keywords： RNA catalysis     RNA structure     catalytic mechanism    

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Anti RNA Viruses Related Biomaterials

Yao Kangde,Yin Yuji,Zhang Baolian,Zhao Liguo

Strategic Study of CAE 2003, Volume 5, Issue 7,   Pages 17-23

Abstract:

The structure, reproduction, replication and transcription of RNA viruses were introduced.Antivirus strategies including design of anti - SARS drugs, RNA interference, DNA vaccine delivery systemThese examples imply the interactions of RNA viruses with proteins, DNA, and polysaccharides.

Keywords： Anti-RNA viruses     protein     DNA     polysaccharide     biomaterials    

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RNA-Based Biocontrols—A New Paradigm in Crop Protection Review

Matthew Bramlett, Geert Plaetinck, Peter Maienfisch

Engineering 2020, Volume 6, Issue 5,   Pages 522-527 doi: 10.1016/j.eng.2019.09.008

Abstract: Over the last years, the RNA interference (RNAi) process has been identified as a very promising newRNA-based active ingredients (AIs) possess a unique mode of action and can be implemented via both geneticRNA-based AIs promise to deliver the selectivity and sustainability desired in future crop protectionresearch progress toward RNA-based biocontrols against the Colorado potato beetle (CPB), corn rootwormMany challenges still exist on the road to the implementation of a broad range of RNA-based products

Keywords： RNA-based biocontrols     RNA interference (RNAi)     Colorado potato beetle (CPB)     Corn rootworm (CRW)     Soy    

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Knockdown of a Specific Circular Non-coding RNA Significantly Suppresses Osteosarcoma Progression Article

Shidong Wang, Hongliang Zhang, Bo Li, Chenglong Chen, Tingting Ren, Yi Huang, Kai Liu, Jingjing Li, Wei Guo

Engineering 2023, Volume 21, Issue 2,   Pages 187-193 doi: 10.1016/j.eng.2021.12.007

Abstract:

Osteosarcoma (OS) is a malignant mesenchymal tissue tumor known to occur in children and adolescents, and pulmonary metastasis often leads to death in these patients. The mechanism underlying OS progression remains unclear. Therefore, identifying new therapeutic targets and treatment modalities for OS is urgently needed. Abnormally expressed non-coding circular RNAs (circRNAs) are crucial for the occurrence and development of OS. The purpose of this study was to explore the expression and role of a novel circRNA circ_000203 in OS and elucidate the underlying mechanism. circ_000203 was demonstrated highly expressed in OS cell lines and tissues, and circ_000203 knockdown significantly inhibited OS progression in vitro and in vivo. Furthermore, we found that circ_000203 is a sponge of miR-26b-5p, an upstream regulator of bone morphogenetic protein receptor 2 (BMPR2). Thus, the overexpression of BMPR2 could reduce the inhibitory effect on OS progression. This indicates that knockdown of circ_000203 suppresses OS progression through microRNA (miRNA)-mediated BMPR2 downregulation. Our findings provide important insights for understanding the occurrence and development of OS. 

Keywords： Non-coding RNA     Osteosarcoma     CircRNA     Molecular mechanism     Knockdown    

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Recent advances in cycloaddition of CO with epoxides: halogen-free catalysis and mechanistic insights

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 12,   Pages 1879-1894 doi: 10.1007/s11705-023-2354-4

Abstract: In this review, we systematically discussed the halogen-free catalysis for cycloaddition of CO2<

Keywords： carbon dioxide     halogen-free catalysis     cyclic carbonate     mechanistic insight    

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Blockage of receptor-interacting protein 2 expression by small interfering RNA in murine macrophages

LIU Hongchun, CAO Zhongwei, JIN Jianjun, WANG Jiyao

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 166-170 doi: 10.1007/s11684-008-0030-1

Abstract: Murine Rip2 small interfering RNA (siRNA) plasmids were constructed and transfected into macrophage and
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Overexpressed long noncoding RNA CRNDE with distinct alternatively spliced isoforms in multiple cancers

Xuefei Ma, Wei Zhang, Rong Zhang, Jingming Li, Shufen Li, Yunlin Ma, Wen Jin, Kankan Wang

Frontiers of Medicine 2019, Volume 13, Issue 3,   Pages 330-343 doi: 10.1007/s11684-017-0557-0

Abstract: CRNDE is a long noncoding RNA with alternative splicing and is implicated in the pathogenesis of several

Keywords： long noncoding RNA     CRNDE     alternative splicing    

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Application of heterogeneous catalysis to biodiesel synthesis using microalgae oil

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 5, doi: 10.1007/s11783-020-1343-9

Abstract:

• Microalgae oil application for biodiesel synthesis is discussed.

Keywords： Biodiesel     Heterogeneous catalysis     Transesterification     Microalgae oil    

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Plasma-catalysis: Is it just a question of scale?

J. Christopher Whitehead

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 2,   Pages 264-273 doi: 10.1007/s11705-019-1794-3

Abstract: It is concluded that plasma-catalysis is best regarded as conventional catalysis perturbed by the presenceThe sometimes used description “plasma-activated catalysis” is an apt one.

Keywords： plasma catalysis     plasma-activated catalysis     non-thermal plasma     CO2 conversion    

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Frontiers of Catalysis Chemistry and Technology

Frontiers of Chemical Science and Engineering 2018, Volume 12, Issue 1,   Pages 1-2 doi: 10.1007/s11705-018-1704-0

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Scaling up of cluster beam deposition technology for catalysis application

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 6,   Pages 1360-1379 doi: 10.1007/s11705-021-2101-7

Abstract: the low throughput of the physical synthesis method has severely constrained its wider adoption for catalysis

Keywords： nanoparticle     cluster     cluster beam deposition     magnetron sputtering     heterogeneous catalysis    

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Preface to special issue on “Advanced Materials and Catalysis”

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 6,   Pages 1357-1359 doi: 10.1007/s11705-021-2119-x

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Potential use of serum HBV RNA in antiviral therapy for chronic hepatitis B in the era of nucleos(t)ide

Fengmin Lu, Jie Wang, Xiangmei Chen, Dongping Xu, Ningshao Xia

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 502-508 doi: 10.1007/s11684-017-0590-z

Abstract: In this review, the RNA virion-like particles of hepatitis B virus (HBV) are integrated into the lifecycle of HBV replication, and the potential significance of serum HBV RNA is systematically describedThe production of HBV RNA virion-like particles should not be blocked by NA; in this regard, serum HBV, with pregenomic RNA origination, can only be transcribed from cccDNA.The clinical status of consistent loss of serum HBV RNA accompanied with low serum HBsAg levels might

Keywords： chronic hepatitis B     serum HBV RNA     nucleos(t)ide analogs     virological response     para-functional cure    

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immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell RNA-seq

Frontiers of Medicine doi: 10.1007/s11684-023-1017-7

Abstract: By conducting single-cell RNA-seq analyses on 26 gliomas, we reported their classification into primitive

Keywords： single-cell RNA-seq     glioma     radial glia     primitive oligodendrocyte precursor cell     immune escape    

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Construction and identification of lentiviral RNA interference vector of rat leptin receptor gene

Zhengjuan LIU, Jie BIAN, Yuchuan WANG, Yongli ZHAO, Dong YAN, Xiaoxia WANG

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 57-60 doi: 10.1007/s11684-009-0003-z

Abstract: The aim of the present study was to construct the lentiviral RNA interference (RNAi) vector of rat OBRb

Keywords： receptors     leptin     RNA interference     lentivirus vector    

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Title Author Date Type Operation

Ribozyme and the mechanisms that underlie RNA catalysis

Timothy J. Wilson,Yijin Liu,David M. J. Lilley

Journal Article

Anti RNA Viruses Related Biomaterials

Yao Kangde,Yin Yuji,Zhang Baolian,Zhao Liguo

Journal Article

RNA-Based Biocontrols—A New Paradigm in Crop Protection

Matthew Bramlett, Geert Plaetinck, Peter Maienfisch

Journal Article

Knockdown of a Specific Circular Non-coding RNA Significantly Suppresses Osteosarcoma Progression

Shidong Wang, Hongliang Zhang, Bo Li, Chenglong Chen, Tingting Ren, Yi Huang, Kai Liu, Jingjing Li, Wei Guo

Journal Article

Recent advances in cycloaddition of CO with epoxides: halogen-free catalysis and mechanistic insights

Journal Article

Blockage of receptor-interacting protein 2 expression by small interfering RNA in murine macrophages

LIU Hongchun, CAO Zhongwei, JIN Jianjun, WANG Jiyao

Journal Article

Overexpressed long noncoding RNA CRNDE with distinct alternatively spliced isoforms in multiple cancers

Xuefei Ma, Wei Zhang, Rong Zhang, Jingming Li, Shufen Li, Yunlin Ma, Wen Jin, Kankan Wang

Journal Article

Application of heterogeneous catalysis to biodiesel synthesis using microalgae oil

Journal Article

Plasma-catalysis: Is it just a question of scale?

J. Christopher Whitehead

Journal Article

Frontiers of Catalysis Chemistry and Technology

Journal Article

Scaling up of cluster beam deposition technology for catalysis application

Journal Article

Preface to special issue on “Advanced Materials and Catalysis”

Journal Article

Potential use of serum HBV RNA in antiviral therapy for chronic hepatitis B in the era of nucleos(t)ide

Fengmin Lu, Jie Wang, Xiangmei Chen, Dongping Xu, Ningshao Xia

Journal Article

immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell RNA-seq

Journal Article

Construction and identification of lentiviral RNA interference vector of rat leptin receptor gene

Zhengjuan LIU, Jie BIAN, Yuchuan WANG, Yongli ZHAO, Dong YAN, Xiaoxia WANG

Journal Article